Nurses who manage wounds understand that maintaining  oxygenation of the tissues  at the wound site is  vital for the promotion of wound healing. It is thought that  ”prolonged hypoxia
may maintain pro-inflammatory conditions and prevent wound healing. Thus, ongoing hypoxia induced by chronic infections, including increased oxygen consumption by activated neutrophils, may actually impede wound healing.”

The following information  can be found in  this great resource by  Gottrup F, Dissemond J, Baines et al. Use of oxygen therapies in wound healing, with special focus on topical and hyperbaric oxygen treatment. J Wound Care, 2017; 26(5), Suppl, S1–S42.  I have enclosed the document below for your information and interest.

  • Topical Oxygen therapy known as TOT can be defined as the “administration of oxygen applied topically over injured tissue by either continuous delivery or pressurised systems. The availability to the wound tissue of topically applied higher pO2 reverses localised hypoxia. This causes both the direct killing of anaerobic bacteria and an enhancement of leukocyte function to address all other pathogen.”
  • Measurement of local tissue oxygenation before and during hyperbaric oxygenation may assist health professionals in identification of patients likely to benefit from HBOT. However, all O2 therapies, including local O2 supply or delivery enhancement by haemoglobin, will benefit from the knowledge of the O2 levels in the proximity of the wound.
  • Measurement of pO2 near the wound, so called transcutaneous oximetry (TCOM), is currently approved as the best surrogate for oxygenation of the wound bed. This measurement strongly depends on several factors, including local perfusion, temperature reactivity, and O2 outflow through the skin layers
  • Technologies available for distribution of topical oxygen in wound healing
    Continuous delivery of non-pressurised oxygen (CDO)
    Low constant pressure oxygen in a contained chamber
    Higher cyclical pressure oxygen
    Oxygen release through dressing or gel
    Oxygen transfer
    Application of oxygen species
  • Different kinds of wound dressing  products are available, either using the release of pure O2 embedded in the dressing or releasing O2 generated by a biochemical reaction in a hydrogel. In the O2 containing
    dressings, pure O2 is embedded, such as in vesicles,and released after the dressing is liquefied by the wound exudate. Continuous O2 release dressings can be used as secondary dressing and release O2
    for up to six days

The document also provides good information on each of the following technologies and how they can assist with wound healing.

  • Oxygen release through dressings or gels
  • Continuous delivery of nonpressurised oxygen
  • Low constant pressure oxygen in a contained chamber
  • Higher cyclical pressure oxygen
  • Oxygen transfer
  • Application of oxygen species
  • Hyperbaric oxygen therapy

You  can download the document here>>

Nurses interested in extending their knowledge in wound management see our Nursing CPD Institute  Wound Management Program – you can pick and choose modules of interest to you! Click here>>

The Nursing CPD Institute  provides great information and CPD  on an array of nursing topics including wound care in a range of easy learning ways including webinars and quizzes on the latest information that Nurses need to know – remember  it was created by Australian Nurses for Nurses!